📊 Interactive Dashboard AI-Simulated · In-Silico Plotly · 11 Charts

Simulation Results Dashboard

Interactive Plotly visualisations of the DT-RL computational framework — explore PK dynamics, tumour trajectories, RL convergence, dose schedules, safety metrics, and the animated side-by-side comparison.

Patients Simulated
3
P1 · P2 · P3
Avg Tumour Reduction (RL)
99.3%
vs 99.3% Fixed
Time-in-Range
100%
All RL patients
AUC Burden Reduction
43%
RL vs Fixed dose
RL Convergence
~350 ep
SAC agent · 500 ep total
Treatment Horizon
180 d
6 cycles · 168 days sim

⚠ All data are in-silico AI-simulated outputs. No human subjects or clinical trials were involved.

Dose & Tumour PK Curves Trajectory & RL Safety & Scatter Dose Heatmap PBPK Distribution ▶ Animated Comparison AUC Burden
📊 Dose & Tumour Reduction

Cumulative Dose Comparison

RL-optimised vs Fixed-dose across 3 patients (mg)

Bar Chart

Tumour Volume Reduction

Initial vs Final tumour volume per patient (cm³)

Bar Chart
💊 Pharmacokinetic Curves

Pharmacokinetic (PK) Concentration Curves

Simulated plasma drug concentration over time — RL-adaptive vs Fixed dosing (3 patients)

📈 Trajectory & RL Convergence

Tumour Volume Trajectory

Digital Twin ODE simulation over 180-day treatment horizon

Time Series

SAC RL Training Convergence

Episode reward over 500 training episodes with rolling average

Convergence
🛡 Safety Metrics

Safety Profile — Radar

Multi-dimensional safety benchmarks: RL vs Fixed dosing

Radar

Dose Efficiency vs ANC Safety

Scatter: cumulative dose (mg) vs final ANC — RL vs Fixed per patient

Scatter
🔥 Dose Schedule Heatmap

RL Dose Schedule Heatmap

Cycle-by-cycle dose intensity per patient — RL-adaptive scheduling across 6 treatment cycles

Heatmap
⚗ PBPK Compartment Distribution

PBPK Compartment Drug Distribution

Simulated drug concentration across physiological compartments at peak (Cmax) for RL-optimised dosing

Bar / Waterfall
▶ Animated Tumour Trajectory Comparison
▶ Animated 180-Day Simulation Plotly Animation

Side-by-Side Tumour Trajectory: RL vs Fixed Dose

Digital Twin Gompertz ODE · 3 virtual patients · Day-by-day animated progression · Press Play or drag the slider

Patients: P1 — High Burden P2 — Low Burden P3 — Intermediate Dotted = Fixed-Dose
P1 — RL vs Fixed
99.8% vs 97.4%
tumour reduction
P2 — RL vs Fixed
99.6% vs 96.5%
tumour reduction
P3 — RL vs Fixed
99.7% vs 96.9%
tumour reduction
Day: 0
P1 RL
P2 RL
P3 RL
|
P1 Fixed
P2 Fixed
P3 Fixed
Left panel = RL · Right panel = Fixed dose
📉 Cumulative Tumour Burden (AUC)

Cumulative Tumour Burden — AUC Comparison

Area Under the Curve (AUC) of tumour volume over 180 days — RL vs Fixed dosing per patient. Lower AUC = less total tumour burden experienced by the patient.

AUC · cm³·day
P1 — AUC Reduction
43.0%
916.1 vs 1607.8 cm³·day
P2 — AUC Reduction
42.2%
564.7 vs 976.6 cm³·day
P3 — AUC Reduction
43.8%
692.3 vs 1230.8 cm³·day